Wylie ER Share: Hospitals & Medical Centers Wylie ER Visit Website 508 S Hwy 78 Wylie, TX 75098 (469) 782-0619 Hours: We are open 24/7 About Map About Stand-alone Emergency Room Directions We are located on the corner of 78 and 544 in Wylie What's Nearby? Distance: 5 10 15 20 25 50 mi.
